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A FUNCTIONAL SCREENING OF ADENOSINE ANALOGUES AT THE ADENOSINE A(2B) RECEPTOR: A SEARCH FOR POTENT AGONISTS

Various adenosine analogues were tested at the adenosine A(2B) receptor. Agonist potencies were determined by measuring the cyclic AMP production in Chinese Hamster Ovary cells expressing human A(2B) receptors. 5′-N-Substituted carboxamidoadenosines were most potent. 5′-N-Ethylcarboxamidoadenosine (...

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Bibliografische gegevens
Hoofdauteurs: de Zwart, Maarten, Link, Regina, von Frijtag Drabbe Künzel, Jacobien K., Cristalli, Gloria, Jacobson, Kenneth A., Townsend-Nicholson, Andrea, IJzerman, Ad P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1998
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459057/
https://ncbi.nlm.nih.gov/pubmed/9708319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07328319808004215
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