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A FUNCTIONAL SCREENING OF ADENOSINE ANALOGUES AT THE ADENOSINE A(2B) RECEPTOR: A SEARCH FOR POTENT AGONISTS

Various adenosine analogues were tested at the adenosine A(2B) receptor. Agonist potencies were determined by measuring the cyclic AMP production in Chinese Hamster Ovary cells expressing human A(2B) receptors. 5′-N-Substituted carboxamidoadenosines were most potent. 5′-N-Ethylcarboxamidoadenosine (...

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Detalhes bibliográficos
Main Authors: de Zwart, Maarten, Link, Regina, von Frijtag Drabbe Künzel, Jacobien K., Cristalli, Gloria, Jacobson, Kenneth A., Townsend-Nicholson, Andrea, IJzerman, Ad P.
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459057/
https://ncbi.nlm.nih.gov/pubmed/9708319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07328319808004215
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