Allosteric modulation, thermodynamics and binding to wild-type and mutant (T277A) adenosine A(1) receptors of LUF5831, a novel nonadenosine-like agonist

1. The interaction of a new nonribose ligand (LUF5831) with the human adenosine A(1) receptor was investigated in the present study. 2. Radioligand binding experiments were performed in the absence and presence of diverse allosteric modulators on both wild-type (wt) and mutant (T277A) adenosine A(1)...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Heitman, Laura H, Mulder-Krieger, Thea, Spanjersberg, Ronald F, von Frijtag Drabbe Künzel, Jacobien K, Dalpiaz, Alessandro, IJzerman, Adriaan P
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2006
Konular:
Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1616979/
https://ncbi.nlm.nih.gov/pubmed/16444290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706655
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller