Putative role of the adenosine A(3) receptor in the antiproliferative action of N(6)-(2-isopentenyl)adenosine

We tested a panel of naturally occurring nucleosides for their affinity towards adenosine receptors. Both N (6)-(2-isopentenyl)adenosine (IPA) and racemic zeatin riboside were shown to be selective human adenosine A(3) receptor (hA(3)R) ligands with affinities in the high nanomolar range (K (i) valu...

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Bibliographic Details
Main Authors: Blad, Clara C., von Frijtag Drabbe Künzel, Jacobien K., de Vries, Henk, Mulder-Krieger, Thea, Bar-Yehuda, Sara, Fishman, Pnina, IJzerman, Adriaan P.
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2011
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224645/
https://ncbi.nlm.nih.gov/pubmed/21720785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-011-9244-9
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