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NMR Solution Structures of Bi-stranded Abasic Site Lesions in DNA

Ionizing radiation produces clustered lesions in DNA. Since the orientation of bi-stranded lesions affects their recognition by DNA repair enzymes, clustered damages are more difficult to process, and thus more toxic, than single oxidative lesions. In order to understand the structural determinants...

詳細記述

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書誌詳細
主要な著者: Hazel, Raphael D., Tian, Kegui, de los Santos, Carlos
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458711/
https://ncbi.nlm.nih.gov/pubmed/18950195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800950t
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