Solution structure of duplex DNA containing an extrahelical abasic site analog determined by NMR spectroscopy and molecular dynamics.

Translesional DNA synthesis past abasic sites proceeds with the preferential incorporation of dAMP opposite the lesion and, depending on the sequence context, one or two base deletions. High-resolution NMR spectroscopy and molecular dynamics simulations were used to determine the three-dimensional s...

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Detalles Bibliográficos
Main Authors: Lin, Z, Hung, K N, Grollman, A P, de los Santos, C
Formato: Artigo
Idioma:Inglês
Publicado: 1998
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC147573/
https://ncbi.nlm.nih.gov/pubmed/9580690
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