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NMR spectroscopy of RNA duplexes containing pseudouridine in supercooled water

We have performed NMR experiments in supercooled water in order to decrease the temperature-dependent exchange of protons in RNA duplexes. NMR spectra of aqueous samples of RNA in bundles of narrow capillaries that were acquired at temperatures as low as −18°C reveal resonances of exchangeable proto...

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Main Authors: SCHROEDER, KERSTEN T., SKALICKY, JACK J., GREENBAUM, NANCY L.
格式: Artigo
語言:Inglês
出版: Copyright 2005 by RNA Society 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370786/
https://ncbi.nlm.nih.gov/pubmed/15987812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2270205
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