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Computational and NMR studies of RNA duplexes with an internal pseudouridine-adenosine base pair
Pseudouridine (Ψ) is the most common chemical modification present in RNA. In general, Ψ increases the thermodynamic stability of RNA. However, the degree of stabilization depends on the sequence and structural context. To explain experimentally observed sequence dependence of the effect of Ψ on the...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6838189/ https://ncbi.nlm.nih.gov/pubmed/31700156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52637-0 |
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