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X-ray Structures of U2 snRNA - Branchpoint Duplexes Containing Conserved Pseudouridines

A pseudouridine-modified region of the U2 small nuclear (sn)RNA anneals with the intronic branchpoint sequence, and positions a bulged adenosine to serve as the nucleophile in the first chemical step of pre-mRNA splicing. We have determined three X-ray structures of RNA oligonucleotides containing t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Lin, Yuan, Kielkopf, Clara L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442566/
https://ncbi.nlm.nih.gov/pubmed/18435545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi7022392
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