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A conserved pseudouridine modification in eukaryotic U2 snRNA induces a change in branch-site architecture.

The removal of noncoding sequences (introns) from eukaryotic precursor mRNA is catalyzed by the spliceosome, a dynamic assembly involving specific and sequential RNA-RNA and RNA-protein interactions. An essential RNA-RNA pairing between the U2 small nuclear (sn)RNA and a complementary consensus sequ...

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Hlavní autoři: Newby, M I, Greenbaum, N L
Médium: Artigo
Jazyk:Inglês
Vydáno: 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370140/
https://ncbi.nlm.nih.gov/pubmed/11424937
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