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The evolutionarily conserved region of the U snRNA export mediator PHAX is a novel RNA-binding domain that is essential for U snRNA export.

In metazoa, a subset of spliceosomal U snRNAs are exported from the nucleus after transcription. This export occurs in a large complex containing a U snRNA, the nuclear cap binding complex (CBC), the leucine-rich nuclear export signal receptor CRM1/Xpo1, RanGTP, and the recently identified phosphopr...

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Bibliografische gegevens
Hoofdauteurs: Segref, A, Mattaj, I W, Ohno, M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2001
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370092/
https://ncbi.nlm.nih.gov/pubmed/11333016
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