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Pseudouridines in and near the branch site recognition region of U2 snRNA are required for snRNP biogenesis and pre-mRNA splicing in Xenopus oocytes

Virtually all uridines in the branch site recognition region (BSRR) of vertebrate U2 are converted into pseudouridines after initial transcription. Here, we report a functional analysis of these modified nucleotides using the Xenopus oocyte reconstitution system. Using site-specific (32)P-labeling a...

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Detalhes bibliográficos
Main Authors: ZHAO, XINLIANG, YU, YI-TAO
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2004 by RNA Society 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370558/
https://ncbi.nlm.nih.gov/pubmed/15037777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5159504
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