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X-ray Structures of U2 snRNA - Branchpoint Duplexes Containing Conserved Pseudouridines
A pseudouridine-modified region of the U2 small nuclear (sn)RNA anneals with the intronic branchpoint sequence, and positions a bulged adenosine to serve as the nucleophile in the first chemical step of pre-mRNA splicing. We have determined three X-ray structures of RNA oligonucleotides containing t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442566/ https://ncbi.nlm.nih.gov/pubmed/18435545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi7022392 |
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