Crystal structure of a model branchpoint-U2 snRNA duplex containing bulged adenosines.

Bulged nucleotides play a variety of important roles in RNA structure and function, frequently forming tertiary interactions and sometimes even participating in RNA catalysis. In pre-mRNA splicing, the U2 snRNA base pairs with the intron branchpoint sequence (BPS) to form a short RNA duplex that con...

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Bibliographic Details
Main Authors: Berglund, J A, Rosbash, M, Schultz, S C
Format: Artigo
Language:Inglês
Published: 2001
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370120/
https://ncbi.nlm.nih.gov/pubmed/11350032
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