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Crystal structures of U6 snRNA-specific terminal uridylyltransferase

The terminal uridylyltransferase, TUT1, builds or repairs the 3′-oligo-uridylylated tail of U6 snRNA. The 3′-oligo-uridylylated tail is the Lsm-binding site for U4/U6 di-snRNP formation and U6 snRNA recycling for pre-mRNA splicing. Here, we report crystallographic and biochemical analyses of human T...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Yamashita, Seisuke, Takagi, Yuko, Nagaike, Takashi, Tomita, Kozo
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467268/
https://ncbi.nlm.nih.gov/pubmed/28589955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15788
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