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Crystal structures of U6 snRNA-specific terminal uridylyltransferase
The terminal uridylyltransferase, TUT1, builds or repairs the 3′-oligo-uridylylated tail of U6 snRNA. The 3′-oligo-uridylylated tail is the Lsm-binding site for U4/U6 di-snRNP formation and U6 snRNA recycling for pre-mRNA splicing. Here, we report crystallographic and biochemical analyses of human T...
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| Gepubliceerd in: | Nat Commun |
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| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5467268/ https://ncbi.nlm.nih.gov/pubmed/28589955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15788 |
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