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Identification, cloning, and functional analysis of the human U6 snRNA-specific terminal uridylyl transferase

Mammalian cells contain a highly specific terminal uridylyl transferase (TUTase) that exclusively accepts U6 snRNA as substrate. This enzyme, termed U6-TUTase, was purified from HeLa cell extracts and analyzed by microsequencing. All sequenced peptides matched a unique human cDNA coding for a previo...

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Detalhes bibliográficos
Main Authors: Trippe, Ralf, Guschina, Elena, Hossbach, Markus, Urlaub, Henning, Lührmann, Reinhard, Benecke, Bernd-Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1524887/
https://ncbi.nlm.nih.gov/pubmed/16790842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.87706
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