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The U11/U12 snRNP 65K protein acts as a molecular bridge, binding the U12 snRNA and U11-59K protein

U11 and U12 interact cooperatively with the 5′ splice site and branch site of pre-mRNA as a stable preformed di-snRNP complex, thereby bridging the 5′ and 3′ ends of the intron within the U12-dependent prespliceosome. To identify proteins contributing to di-snRNP formation and intron bridging, we in...

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Sonraí Bibleagrafaíochta
Main Authors: Benecke, Heike, Lührmann, Reinhard, Will, Cindy L
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2005
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201347/
https://ncbi.nlm.nih.gov/pubmed/16096647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600765
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