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The U11/U12 snRNP 65K protein acts as a molecular bridge, binding the U12 snRNA and U11-59K protein
U11 and U12 interact cooperatively with the 5′ splice site and branch site of pre-mRNA as a stable preformed di-snRNP complex, thereby bridging the 5′ and 3′ ends of the intron within the U12-dependent prespliceosome. To identify proteins contributing to di-snRNP formation and intron bridging, we in...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201347/ https://ncbi.nlm.nih.gov/pubmed/16096647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600765 |
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