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Evolutionarily conserved exon definition interactions with U11 snRNP mediate alternative splicing regulation on U11–48K and U11/U12–65K genes

Many splicing regulators bind to their own pre-mRNAs to induce alternative splicing that leads to formation of unstable mRNA isoforms. This provides an autoregulatory feedback mechanism that regulates the cellular homeostasis of these factors. We have described such an autoregulatory mechanism for t...

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Bibliografske podrobnosti
izdano v:RNA Biol
Main Authors: Niemelä, Elina H, Verbeeren, Jens, Singha, Prosanta, Nurmi, Visa, Frilander, Mikko J
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829294/
https://ncbi.nlm.nih.gov/pubmed/26479860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1096489
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