Evolutionarily conserved exon definition interactions with U11 snRNP mediate alternative splicing regulation on U11–48K and U11/U12–65K genes

Many splicing regulators bind to their own pre-mRNAs to induce alternative splicing that leads to formation of unstable mRNA isoforms. This provides an autoregulatory feedback mechanism that regulates the cellular homeostasis of these factors. We have described such an autoregulatory mechanism for t...

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Foilsithe in:RNA Biol
Main Authors: Niemelä, Elina H, Verbeeren, Jens, Singha, Prosanta, Nurmi, Visa, Frilander, Mikko J
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2015
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829294/
https://ncbi.nlm.nih.gov/pubmed/26479860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1096489
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