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The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome
U11 and U12 snRNPs bind U12-type pre-mRNAs as a preformed di-snRNP complex, simultaneously recognizing the 5′ splice site and branchpoint sequence. Thus, within the U12-type prespliceosome, U11/U12 components form a molecular bridge connecting both ends of the intron. We have affinity purified human...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Copyright 2004 by RNA Society
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370585/ https://ncbi.nlm.nih.gov/pubmed/15146077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7320604 |
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