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Functional spliceosomal A complexes can be assembled in vitro in the absence of a penta-snRNP
Two different models currently exist for the assembly pathway of the spliceosome, namely, the traditional model, in which spliceosomal snRNPs associate in a stepwise, ordered manner with the pre-mRNA, and the holospliceosome model, in which all spliceosomal snRNPs preassemble into a penta-snRNP comp...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1557700/ https://ncbi.nlm.nih.gov/pubmed/16880538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.120606 |
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