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Functional spliceosomal A complexes can be assembled in vitro in the absence of a penta-snRNP

Two different models currently exist for the assembly pathway of the spliceosome, namely, the traditional model, in which spliceosomal snRNPs associate in a stepwise, ordered manner with the pre-mRNA, and the holospliceosome model, in which all spliceosomal snRNPs preassemble into a penta-snRNP comp...

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Autori principali: Behzadnia, Nastaran, Hartmuth, Klaus, Will, Cindy L., Lührmann, Reinhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557700/
https://ncbi.nlm.nih.gov/pubmed/16880538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.120606
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