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Mechanistic insights into m(6)A modification of U6 snRNA by human METTL16
The N(6)-methyladenosine modification at position 43 (m(6)A43) of U6 snRNA is catalyzed by METTL16, and is important for the 5′-splice site recognition by U6 snRNA during pre-mRNA splicing. Human METTL16 consists of the N-terminal methyltransferase domain (MTD) and the C-terminal vertebrate conserve...
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| Publicado en: | Nucleic Acids Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7229813/ https://ncbi.nlm.nih.gov/pubmed/32266935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa227 |
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