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The U6 snRNA m(6)A methyltransferase METTL16 regulates SAM synthetase intron retention
Maintenance of proper levels of the methyl donor S-adenosylmethionine (SAM) is critical for a wide variety of biological processes. We demonstrate that the N(6)-adenosine methyltransferase METTL16 regulates expression of human MAT2A, which encodes the SAM synthetase expressed in most cells. Upon SAM...
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| Publicado no: | Cell |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5502809/ https://ncbi.nlm.nih.gov/pubmed/28525753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.05.003 |
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