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NMR Solution Structures of Bi-stranded Abasic Site Lesions in DNA
Ionizing radiation produces clustered lesions in DNA. Since the orientation of bi-stranded lesions affects their recognition by DNA repair enzymes, clustered damages are more difficult to process, and thus more toxic, than single oxidative lesions. In order to understand the structural determinants...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458711/ https://ncbi.nlm.nih.gov/pubmed/18950195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800950t |
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