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NMR Solution Structures of Clustered Abasic Site Lesions in DNA: Structural Differences between 3’-Staggered (−3) and 5’-Staggered (+3) Bistranded Lesions
Ionizing radiation produces a distinctive pattern of bistranded clustered lesions in DNA. A relatively low number of clustered lesions may be lethal to cells when compared to a larger number of single lesions. Enzyme cleavage experiments suggest that the orientation of bistranded lesions causes diff...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3017401/ https://ncbi.nlm.nih.gov/pubmed/20825249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101021e |
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