טוען...

1-(Fluoroalkylidene)-1,1-bisphosphonic Acids are Potent and Selective Inhibitors of the Enzymatic Activity of Toxoplasma gondii Farnesyl Pyrophosphate Synthase

α-Fluorinated-1,1-bisphosphonic acids derived from fatty acids were designed, synthesized and biologically evaluated against Trypanosoma cruzi, the etiologic agent of Chagas disease and against Toxoplasma gondii, the responsible agent of toxoplasmosis and also towards the target parasitic enzymes fa...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Szajnman, Sergio H., Rosso, Valeria S., Malayil, Leena, Smith, Alyssa, Moreno, Silvia N. J., Docampo, Roberto, Rodriguez, Juan B.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458512/
https://ncbi.nlm.nih.gov/pubmed/22215028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1ob06602a
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