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Targeting the Mitogen-Activated Protein Kinase RAS-RAF Signaling Pathway in Cancer Therapy

INTRODUCTION: The mitogen-activated protein kinase (MAPK) pathway comprises several key signaling components and phosphorylation events that play important role in tumorigenesis. These activated kinases transmit extracellular signals that regulate cell growth, differentiation, proliferation, apoptos...

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Detalhes bibliográficos
Main Authors: Santarpia, Libero, Lippman, Scott L., El-Naggar, Adel K
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457779/
https://ncbi.nlm.nih.gov/pubmed/22239440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2011.645805
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