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Targeting the Mitogen-Activated Protein Kinase RAS-RAF Signaling Pathway in Cancer Therapy

INTRODUCTION: The mitogen-activated protein kinase (MAPK) pathway comprises several key signaling components and phosphorylation events that play important role in tumorigenesis. These activated kinases transmit extracellular signals that regulate cell growth, differentiation, proliferation, apoptos...

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Bibliografiska uppgifter
Huvudupphovsmän: Santarpia, Libero, Lippman, Scott L., El-Naggar, Adel K
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457779/
https://ncbi.nlm.nih.gov/pubmed/22239440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2011.645805
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