Role of Ca2+ and cyclic AMP in the regulation of the production of prostacyclin by the vascular endothelium.

Incubation of primary monolayer cultures of human umbilical vein endothelial cells with buffer, thrombin (0.5 unit/ml), ionophore A23187 (10 microM), arachidonic acid (20 microM), prostaglandin H2 (PGH2) (4 microM) resulted in prostacyclin (PGI2) production in nanomolar quantities to the extent of 3...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Brotherton, A F, Hoak, J C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1982
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345770/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6281772/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.2.495
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