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Role of Ca2+ and cyclic AMP in the regulation of the production of prostacyclin by the vascular endothelium.

Incubation of primary monolayer cultures of human umbilical vein endothelial cells with buffer, thrombin (0.5 unit/ml), ionophore A23187 (10 microM), arachidonic acid (20 microM), prostaglandin H2 (PGH2) (4 microM) resulted in prostacyclin (PGI2) production in nanomolar quantities to the extent of 3...

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Autors principals: Brotherton, A F, Hoak, J C
Format: Artigo
Idioma:Inglês
Publicat: 1982
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC345770/
https://ncbi.nlm.nih.gov/pubmed/6281772
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