Role of Ca2+ and cyclic AMP in the regulation of the production of prostacyclin by the vascular endothelium.

Incubation of primary monolayer cultures of human umbilical vein endothelial cells with buffer, thrombin (0.5 unit/ml), ionophore A23187 (10 microM), arachidonic acid (20 microM), prostaglandin H2 (PGH2) (4 microM) resulted in prostacyclin (PGI2) production in nanomolar quantities to the extent of 3...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Brotherton, A F, Hoak, J C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1982
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345770/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6281772/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.2.495
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