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Indotecan (LMP400) and AM13-55: Two Novel Indenoisoquinolines Show Potential for Treating Visceral Leishmaniasis

Visceral leishmaniasis is an emerging neglected tropical disease (NTD) caused by the protozoan Leishmania infantum in the countries bordering the Mediterranean Basin. Currently there is no effective vaccine against this disease, and the therapeutic approach is based on toxic derivatives of Sb(V). Th...

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Main Authors: Balaña-Fouce, Rafael, Prada, Christopher F., Requena, José María, Cushman, Mark, Pommier, Yves, Álvarez-Velilla, Raquel, Escudero-Martínez, José Miguel, Calvo-Álvarez, Estefania, Pérez-Pertejo, Yolanda, Reguera, Rosa M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457409/
https://ncbi.nlm.nih.gov/pubmed/22850521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00499-12
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