Indotecan (LMP400) and AM13-55: Two Novel Indenoisoquinolines Show Potential for Treating Visceral Leishmaniasis

Visceral leishmaniasis is an emerging neglected tropical disease (NTD) caused by the protozoan Leishmania infantum in the countries bordering the Mediterranean Basin. Currently there is no effective vaccine against this disease, and the therapeutic approach is based on toxic derivatives of Sb(V). Th...

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Detalhes bibliográficos
Main Authors: Balaña-Fouce, Rafael, Prada, Christopher F., Requena, José María, Cushman, Mark, Pommier, Yves, Álvarez-Velilla, Raquel, Escudero-Martínez, José Miguel, Calvo-Álvarez, Estefania, Pérez-Pertejo, Yolanda, Reguera, Rosa M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457409/
https://ncbi.nlm.nih.gov/pubmed/22850521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00499-12
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