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Indotecan (LMP400) and AM13-55: Two Novel Indenoisoquinolines Show Potential for Treating Visceral Leishmaniasis

Visceral leishmaniasis is an emerging neglected tropical disease (NTD) caused by the protozoan Leishmania infantum in the countries bordering the Mediterranean Basin. Currently there is no effective vaccine against this disease, and the therapeutic approach is based on toxic derivatives of Sb(V). Th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Balaña-Fouce, Rafael, Prada, Christopher F., Requena, José María, Cushman, Mark, Pommier, Yves, Álvarez-Velilla, Raquel, Escudero-Martínez, José Miguel, Calvo-Álvarez, Estefania, Pérez-Pertejo, Yolanda, Reguera, Rosa M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457409/
https://ncbi.nlm.nih.gov/pubmed/22850521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00499-12
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