β1 Integrin NPXY Motifs Regulate Kidney Collecting-Duct Development and Maintenance by Induced-Fit Interactions with Cytosolic Proteins

Loss of β1 integrin expression inhibits renal collecting-system development. Two highly conserved NPXY motifs in the distal β1 tail regulate integrin function by associating with phosphtyrosine binding (PTB) proteins, such as talin and kindlin. Here, we define the roles of these two tyrosines in col...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Mathew, Sijo, Lu, Zhenwei, Palamuttam, Riya J., Mernaugh, Glenda, Hadziselimovic, Arina, Chen, Jiang, Bulus, Nada, Gewin, Leslie S., Voehler, Markus, Meves, Alexander, Ballestrem, Christoph, Fässler, Reinhard, Pozzi, Ambra, Sanders, Charles R., Zent, Roy
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457338/
https://ncbi.nlm.nih.gov/pubmed/22869523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00568-12
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge