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β1 Integrin NPXY Motifs Regulate Kidney Collecting-Duct Development and Maintenance by Induced-Fit Interactions with Cytosolic Proteins

Loss of β1 integrin expression inhibits renal collecting-system development. Two highly conserved NPXY motifs in the distal β1 tail regulate integrin function by associating with phosphtyrosine binding (PTB) proteins, such as talin and kindlin. Here, we define the roles of these two tyrosines in col...

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Detaylı Bibliyografya
Asıl Yazarlar: Mathew, Sijo, Lu, Zhenwei, Palamuttam, Riya J., Mernaugh, Glenda, Hadziselimovic, Arina, Chen, Jiang, Bulus, Nada, Gewin, Leslie S., Voehler, Markus, Meves, Alexander, Ballestrem, Christoph, Fässler, Reinhard, Pozzi, Ambra, Sanders, Charles R., Zent, Roy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457338/
https://ncbi.nlm.nih.gov/pubmed/22869523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00568-12
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