Comparable Fitness and Transmissibility between Oseltamivir-Resistant Pandemic 2009 and Seasonal H1N1 Influenza Viruses with the H275Y Neuraminidase Mutation

Limited antiviral compounds are available for the control of influenza, and the emergence of resistant variants would further narrow the options for defense. The H275Y neuraminidase (NA) mutation, which confers resistance to oseltamivir carboxylate, has been identified among the seasonal H1N1 and 20...

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Detalhes bibliográficos
Main Authors: Wong, Diana D. Y., Choy, Ka-Tim, Chan, Renee W. Y., Sia, Sin Fun, Chiu, Hsin-Ping, Cheung, Peter P. H., Chan, Michael C. W., Peiris, J. S. Malik, Yen, Hui-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457312/
https://ncbi.nlm.nih.gov/pubmed/22811535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00985-12
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