Comparable Fitness and Transmissibility between Oseltamivir-Resistant Pandemic 2009 and Seasonal H1N1 Influenza Viruses with the H275Y Neuraminidase Mutation

Limited antiviral compounds are available for the control of influenza, and the emergence of resistant variants would further narrow the options for defense. The H275Y neuraminidase (NA) mutation, which confers resistance to oseltamivir carboxylate, has been identified among the seasonal H1N1 and 20...

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Bibliografische gegevens
Hoofdauteurs: Wong, Diana D. Y., Choy, Ka-Tim, Chan, Renee W. Y., Sia, Sin Fun, Chiu, Hsin-Ping, Cheung, Peter P. H., Chan, Michael C. W., Peiris, J. S. Malik, Yen, Hui-Ling
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2012
Onderwerpen:
Vaccines and Antiviral Agents
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457312/
https://ncbi.nlm.nih.gov/pubmed/22811535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00985-12
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