Comparable Fitness and Transmissibility between Oseltamivir-Resistant Pandemic 2009 and Seasonal H1N1 Influenza Viruses with the H275Y Neuraminidase Mutation

Limited antiviral compounds are available for the control of influenza, and the emergence of resistant variants would further narrow the options for defense. The H275Y neuraminidase (NA) mutation, which confers resistance to oseltamivir carboxylate, has been identified among the seasonal H1N1 and 20...

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Bibliographic Details
Main Authors: Wong, Diana D. Y., Choy, Ka-Tim, Chan, Renee W. Y., Sia, Sin Fun, Chiu, Hsin-Ping, Cheung, Peter P. H., Chan, Michael C. W., Peiris, J. S. Malik, Yen, Hui-Ling
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457312/
https://ncbi.nlm.nih.gov/pubmed/22811535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00985-12
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