Increased Genetic and Phenotypic Stability of a Promising Live-Attenuated Respiratory Syncytial Virus Vaccine Candidate by Reverse Genetics

Human respiratory syncytial virus (RSV) is the most important viral cause of serious pediatric respiratory illness worldwide. Currently, the most promising live-attenuated vaccine candidate is a temperature-sensitive (ts) cDNA-derived virus named rA2cp248/404/1030ΔSH, in reference to its set of atte...

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Hlavní autoři: Luongo, Cindy, Winter, Christine C., Collins, Peter L., Buchholz, Ursula J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457269/
https://ncbi.nlm.nih.gov/pubmed/22837193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01227-12
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