Increased Genetic and Phenotypic Stability of a Promising Live-Attenuated Respiratory Syncytial Virus Vaccine Candidate by Reverse Genetics

Human respiratory syncytial virus (RSV) is the most important viral cause of serious pediatric respiratory illness worldwide. Currently, the most promising live-attenuated vaccine candidate is a temperature-sensitive (ts) cDNA-derived virus named rA2cp248/404/1030ΔSH, in reference to its set of atte...

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Detalhes bibliográficos
Main Authors: Luongo, Cindy, Winter, Christine C., Collins, Peter L., Buchholz, Ursula J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457269/
https://ncbi.nlm.nih.gov/pubmed/22837193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01227-12
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