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Cytoplasmic Trafficking, Endosomal Escape, and Perinuclear Accumulation of Adeno-Associated Virus Type 2 Particles Are Facilitated by Microtubule Network

Understanding adeno-associated virus (AAV) trafficking is critical to advance our knowledge of AAV biology and exploit novel aspects of vector development. Similar to the case for most DNA viruses, after receptor binding and entry, AAV traverses the cytoplasm and deposits the viral genome in the cel...

詳細記述

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書誌詳細
主要な著者: Xiao, Ping-Jie, Samulski, R. Jude
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457265/
https://ncbi.nlm.nih.gov/pubmed/22811523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00935-12
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