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Endosomal Trafficking of Nanoformulated Antiretroviral Therapy Facilitates Drug Particle Carriage and HIV Clearance

Limitations of antiretroviral therapy (ART) include poor patient adherence, drug toxicities, viral resistance, and failure to penetrate viral reservoirs. Recent developments in nanoformulated ART (nanoART) could overcome such limitations. To this end, we now report a novel effect of nanoART that fac...

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Detalhes bibliográficos
Main Authors: Guo, Dongwei, Zhang, Gang, Wysocki, Tadeusz A., Wysocki, Beata J., Gelbard, Harris A., Liu, Xin-Ming, McMillan, JoEllyn M., Gendelman, Howard E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136325/
https://ncbi.nlm.nih.gov/pubmed/24920821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01557-14
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