Endosomal Trafficking of Nanoformulated Antiretroviral Therapy Facilitates Drug Particle Carriage and HIV Clearance

Limitations of antiretroviral therapy (ART) include poor patient adherence, drug toxicities, viral resistance, and failure to penetrate viral reservoirs. Recent developments in nanoformulated ART (nanoART) could overcome such limitations. To this end, we now report a novel effect of nanoART that fac...

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Main Authors: Guo, Dongwei, Zhang, Gang, Wysocki, Tadeusz A., Wysocki, Beata J., Gelbard, Harris A., Liu, Xin-Ming, McMillan, JoEllyn M., Gendelman, Howard E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136325/
https://ncbi.nlm.nih.gov/pubmed/24920821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01557-14
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