Autophagy facilitates macrophage depots of sustained-release nanoformulated antiretroviral drugs

Long-acting anti-HIV products can substantively change the standard of care for patients with HIV/AIDS. To this end, hydrophobic antiretroviral drugs (ARVs) were recently developed for parenteral administration at monthly or longer intervals. While shorter-acting hydrophilic drugs can be made into n...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Gnanadhas, Divya Prakash, Dash, Prasanta K., Sillman, Brady, Bade, Aditya N., Lin, Zhiyi, Palandri, Diana L., Gautam, Nagsen, Alnouti, Yazen, Gelbard, Harris A., McMillan, JoEllyn, Mosley, R. Lee, Edagwa, Benson, Gendelman, Howard E., Gorantla, Santhi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330738/
https://ncbi.nlm.nih.gov/pubmed/28134625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90025
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