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Mitochondrial oxidant generation and oxidative damage in Ames dwarf and GH transgenic mice

Aging is associated with an accumulation of oxidative damage to proteins, lipids and DNA. Cellular mechanisms designed to prevent oxidative damage decline with aging and in diseases associated with aging. A long-lived mouse, the Ames dwarf, exhibits growth hormone deficiency and heightened antioxida...

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Bibliografiska uppgifter
Huvudupphovsmän: Brown-Borg, Holly, Johnson, W. Thomas, Rakoczy, Sharlene, Romanick, Mark
Materialtyp: Artigo
Språk:Inglês
Publicerad: Kluwer Academic Publishers 2001
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3455482/
https://ncbi.nlm.nih.gov/pubmed/23604879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-001-0012-6
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