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Mitochondrial oxidant generation and oxidative damage in Ames dwarf and GH transgenic mice
Aging is associated with an accumulation of oxidative damage to proteins, lipids and DNA. Cellular mechanisms designed to prevent oxidative damage decline with aging and in diseases associated with aging. A long-lived mouse, the Ames dwarf, exhibits growth hormone deficiency and heightened antioxida...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Kluwer Academic Publishers
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3455482/ https://ncbi.nlm.nih.gov/pubmed/23604879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-001-0012-6 |
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