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Expression of oxidative phosphorylation components in mitochondria of long-living Ames dwarf mice

Reduced signaling of the growth hormone (GH)/insulin-like growth factor-1 (IGF-1) pathway is associated with extended life span in several species. Ames dwarf mice are GH-deficient and live >50% longer than wild-type littermates. Previously, we have shown that tissues from Ames mice exhibit eleva...

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Detalhes bibliográficos
Main Authors: Brown-Borg, Holly M., Johnson, W. Thomas, Rakoczy, Sharlene G.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260352/
https://ncbi.nlm.nih.gov/pubmed/21327718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-011-9212-x
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