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Growth Hormone Alters the Glutathione S-Transferase and Mitochondrial Thioredoxin Systems in Long-Living Ames Dwarf Mice

Ames dwarf mice are deficient in growth hormone (GH), prolactin, and thyroid-stimulating hormone and live significantly longer than their wild-type (WT) siblings. The lack of GH is associated with stress resistance and increased longevity. However, the mechanism underlying GH’s actions on cellular s...

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Detalhes bibliográficos
Main Authors: Rojanathammanee, Lalida, Rakoczy, Sharlene, Brown-Borg, Holly M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172038/
https://ncbi.nlm.nih.gov/pubmed/24285747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glt178
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