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Mitochondrial oxidant generation and oxidative damage in Ames dwarf and GH transgenic mice

Aging is associated with an accumulation of oxidative damage to proteins, lipids and DNA. Cellular mechanisms designed to prevent oxidative damage decline with aging and in diseases associated with aging. A long-lived mouse, the Ames dwarf, exhibits growth hormone deficiency and heightened antioxida...

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書誌詳細
主要な著者: Brown-Borg, Holly, Johnson, W. Thomas, Rakoczy, Sharlene, Romanick, Mark
フォーマット: Artigo
言語:Inglês
出版事項: Kluwer Academic Publishers 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3455482/
https://ncbi.nlm.nih.gov/pubmed/23604879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-001-0012-6
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