Comparative Oncogenomics Implicates the Neurofibromin 1 Gene (NF1) as a Breast Cancer Driver

Identifying genomic alterations driving breast cancer is complicated by tumor diversity and genetic heterogeneity. Relevant mouse models are powerful for untangling this problem because such heterogeneity can be controlled. Inbred Chaos3 mice exhibit high levels of genomic instability leading to mam...

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Detalhes bibliográficos
Main Authors: Wallace, Marsha D., Pfefferle, Adam D., Shen, Lishuang, McNairn, Adrian J., Cerami, Ethan G., Fallon, Barbara L., Rinaldi, Vera D., Southard, Teresa L., Perou, Charles M., Schimenti, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2012
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454871/
https://ncbi.nlm.nih.gov/pubmed/22851646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.142802
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